
Argireline
INCI: Acetyl Hexapeptide-8
Can make fine lines less visible
Good evidence: randomised trials
At a glance
- Suits
- Normal, dry and mature skin with fine lines
- Helps with
- Fine lines, Smoother skin
- Pairs well with
- Hyaluronic acid, Vitamin A, Niacinamide
- Found in
- 2 ECOOKING products
What can Argireline help with?
Fine lines
In a randomised, placebo-controlled study with 60 people, lines around the eyes became less visible after 4 weeks.[1]
Smoother skin
In the same four-week study, the skin’s surface around the eyes became measurably less rough in the group using Argireline. No significant change was measured in the group using cream without Argireline.[1]
How it works
How to use it
- Apply the product to cleansed skin.
- Only use it around the eyes if the product is intended for that area.
- Can be used in the same routine as retinol and hyaluronic acid.
Products with Argireline
Frequently asked questions
Argireline is the trade name for acetyl hexapeptide-8, a peptide used in skincare for expression lines.
No. Argireline is applied to the skin and has been studied for its effect on visible lines. It is not the same as Botox, and studies do not show a comparable effect.
Peptides are short chains of amino acids. Different peptides are used for different purposes in skincare – Argireline is one intended for expression lines.
Argireline (acetyl hexapeptide-8) is found in our Super Serum and Night Cream.
Yes. A product with Argireline can be part of both your morning and evening routine.
Sources
- The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study (American journal of clinical dermatology, 2013)
- Acetyl Hexapeptide-8 in Cosmeceuticals-A Review of Skin Permeability and Efficacy (International journal of molecular sciences, 2025)