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Argireline

Argireline

INCI: Acetyl Hexapeptide-8

Can make fine lines less visible

Good evidence: randomised trials

At a glance

Suits
Normal, dry and mature skin with fine lines

What can Argireline help with?

Fine lines

In a randomised, placebo-controlled study with 60 people, lines around the eyes became less visible after 4 weeks.[1]

Smoother skin

In the same four-week study, the skin’s surface around the eyes became measurably less rough in the group using Argireline. No significant change was measured in the group using cream without Argireline.[1]

How it works

Argireline is the name of the ingredient acetyl hexapeptide-8. It is a peptide, a short chain of amino acids, which are also the building blocks of proteins. The ingredient is made in a laboratory.

Argireline is used in serums and creams that focus on fine lines. It is included alongside other caring ingredients in the finished product.

How to use it

  • Apply the product to cleansed skin.
  • Only use it around the eyes if the product is intended for that area.
  • Can be used in the same routine as retinol and hyaluronic acid.

Products with Argireline

  • Night Cream

    Night-time face cream that moisturises, firms and reduces fine lines and wrin...

    2 scents2 sizes
  • Super Serum

    Fragrance-free anti-ageing serum that firms, reduces fine lines and wrinkles,...

    20 ml50 ml10 ml
See all 2 products with Argireline

Frequently asked questions

Sources

The sources are a randomised trial with 60 participants over four weeks[1] and a review article from 2025.[2] They examine Argireline in skincare, including visible lines and absorption into the skin.

  1. The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study (American journal of clinical dermatology, 2013)
  2. Acetyl Hexapeptide-8 in Cosmeceuticals-A Review of Skin Permeability and Efficacy (International journal of molecular sciences, 2025)

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