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Peptides

Peptides

INCI: Acetyl Hexapeptide-8, Acetyl Hexapeptide-49, Acetyl Hexylpeptide-49, Acetyl Hexapeptide-1, Palmitoyl Tripeptide-5, Tripeptide-10 Citrulline, Biotinoyl Tripeptide-1, Tripeptide-1, Acetyl Tetrapeptide-3, Tetrapeptide-1

Can make fine lines less visible

Good evidence: randomised trials

At a glance

Suits
All skin types, including mature and sensitive skin
Helps with
Fine lines, Wrinkles

What can peptides help with?

Fine lines

Argireline made lines around the eyes less visible after four weeks in a placebo-controlled study with 60 people.[3]

Wrinkles

A cream with a signal peptide (palmitoyl pentapeptide-4) resulted in fewer visible wrinkles and fine lines after 12 weeks than the same cream without it.[4]

Read our guide to peptides

How it works

Peptides are short chains of amino acids, the same building blocks that proteins such as collagen and elastin are made of. In skincare, peptides are made in a laboratory for a specific purpose.

Peptides are typically divided into three groups: signal peptides, which are developed to support the skin’s own collagen production, peptides such as Argireline, which are developed to reduce the small movements behind expression lines, and carrier peptides, which deliver a mineral such as copper to the skin. How well a peptide works depends on the individual peptide and how well it penetrates the skin.

How to use it

  • Use your peptide serum or cream on cleansed skin morning and evening.
  • Can be combined with hyaluronic acid, niacinamide and retinol.
  • If you use copper peptides with vitamin C, follow the product instructions.
  • Use peptides consistently for at least two to three months.

Products with peptides

  • Night Cream

    Night-time face cream that moisturises, firms and reduces fine lines and wrin...

    2 scents2 sizes
  • Peptide Volume Mascara

    Gentle, fragrance-free volume mascara for sensitive eyes that gives lashes fu...

    2 colours
  • Super Serum

    Fragrance-free anti-ageing serum that firms, reduces fine lines and wrinkles,...

    20 ml50 ml10 ml
  • Energizing Eye Cream

    Fragrance-free eye cream for wrinkles and dark circles that firms, moisturise...

    15 ml
  • Multi Balm Stick 4 g

    Our Multi Balm Stick 4 g, also known as Multi Balm, a moisturising balm for v...

    4 g
  • Eyelash serum 5 ml

    Our eyelash serum 5 ml gives longer, thicker and fuller lashes, controls hair...

    5 ml
  • Multi Balm

    Fragrance-free balm for very dry skin that restores the skin barrier and soot...

    75 ml30 ml
  • Neck & Décolleté Firming Cream

    Fragrance-free, firming cream for the neck and chest that reduces wrinkles an...

    50 ml
See all 9 products with peptides

Frequently asked questions

Sources

The sources are two controlled studies of specific peptides on fine lines[3][4] and three review articles on peptides in skincare and how well they penetrate the skin.[1][2][5]

  1. Role of topical peptides in preventing or treating aged skin (International journal of cosmetic science, 2009)
  2. Cosmeceutical Peptides in the Framework of Sustainable Wellness Economy (Frontiers in chemistry, 2020)
  3. The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study (American journal of clinical dermatology, 2013)
  4. Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin (International journal of cosmetic science, 2005)
  5. Acetyl Hexapeptide-8 in Cosmeceuticals - A Review of Skin Permeability and Efficacy (International journal of molecular sciences, 2025)

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